Home

Data from more than 1,000 patients presented during the virtual Society for Cardiovascular Angiography and Interventions (SCAI) 2020 Scientific Sessions (14–16 May, Eastern Time) demonstrates Impella (Abiomed) reduced in-hospital mortality when placed before a non-emergent percutaneous coronary intervention (PCI) is performed. According to a press release, the research found that, in the setting of high-risk PCI, when Impella is placed pre-PCI, it is associated with a 10 times reduction of in-hospital mortality, compared to when Impella is placed during “bailout” PCI.

The data presented were from an adjunct study of PROTECT III; the ongoing, prospective FDA post-approval study for Impella in high-risk PCI. The research is authored by William O’Neill (Center for Structural Heart Disease, Henry Ford Hospital, Detroit, USA) and Jeffrey W Moses (Columbia University Medical Center, New York, USA). They state: “Support with Impella in haemodynamically stable patients undergoing non-emergent PCI, also termed Protected PCI, is now a well-established indication in a selective patient population at high risk for haemodynamic collapse during PCI. However, some physicians may eschew preventive haemodynamic support and prefer a bailout strategy should hemodynamic collapse occur.” The study aimed to quantify the risk of such a bailout strategy.

The study analysed 1,028 patients supported with Impella 2.5 or Impella CP (971 in Protected PCI group and 57 in bailout group). In the bailout group, females were more prevalent (50.9% versus 27.2%; p=0.0002), the median baseline left ventricular ejection fraction was significantly higher (40% versus30%; p<0.0001), heart failure was less prevalent (42.1% versus 56.9%; p=0.039), and left main disease was less prevalent (40.0% versus 56.1%; p=0.03). In summary, the bailout group had a higher percentage of women, the patients were younger, and had a higher ejection fraction with less heart failure. Despite these differences the study found:

In-hospital mortality was significantly higher in the bailout group compared to the Protected PCI group, respectively (49.1% versus 4.3%; p<0.0001). The difference in mortality was significant across patients experiencing haemodynamic collapse secondary to refractory hypotension or coronary perforation/dissection.

O’Neill comments: “Failure to prospectively identify patients who may experience hemodynamic collapse during non-emergent PCI leads to excessive in-hospital mortality. This data shows that Impella support prior to initiation of the PCI can reduce this risk.”

Source CardiovascularNews

Duc Tin Clinic

Chia sẽ qua facebook bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Chia sẽ qua google bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Chia sẽ qua twitter bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Chia sẽ qua MySpace bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Chia sẽ qua LinkedIn bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Chia sẽ qua stumbleupon bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Chia sẽ qua icio bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Chia sẽ qua digg bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Chia sẽ qua yahoo bài: PROTECT III shows placing Impella prior to high-risk PCI associated with lower mortality

Tin tức liên quan

Enrolment reaches midway point in trial of Early Bird bleed monitoring system

Eight-fold increased risk of heart attack seen in patients with subclinical obstructive coronary atherosclerosis

ACC 2023: REVIVED-BCIS-2 results challenge “long-held beliefs” on myocardial viability testing prior to PCI

Blood pressure successfully cut in RADIANCE II ultrasound renal denervation trial

New data examine mortality rates and cardiac damage in early-stage aortic stenosis patients

SUPPORT CONSULTANT

Make an Appointment

I am Nguyen Thanh Sang, born in 1990. Since the examination and treatment at the clinic Duc Tin, I am very grateful to the Doctor for explaining and sharing about my illness. During the treatment time in the clinic I was very caring staff of the clinic. Now my illness has improved in a good way. Expect more and more clinic to be able to save many patients.

I sincerely thank you !. Tel: 0938303275

Huynh Thi Muoi, born in 1940, was examined and treated at Duc Tin Clinic. I am very pleased about how to serve and care patients of the clinic. The doctor is committed to explaining and sharing with the patient.

Huynh Thi Muoi sincerely thank you! Phone number: 0972868746

As I said Duc Tin surgical clinin is where my family trust, hope to visit. Physicians caring, thoughtful, gentle to the patient. Nurses and staff clinic polite, cheerful and thoughtful. This clinic clean, sterile, so I would love to. Tel: +84949914060.

The doctor is very caring, attentive and very gentle nurse, courteous, affable with me. The clinic is clean, comfortable, polite. I enjoyed this faith. Every visit I was very relieved disease. Tel: 0839820792.

I was patient, had to clinics of Dr. Le Duc Tin. I see very conscientious doctor patient care, answer any questions and very dedicated staff from the receptionist to the children tested, nursing. Clinics very clean and spacious. I'm very satisfied. Tel: +841227880829.